Protein name:
Multidrug resistance-associated protein 1 ;
Alternative:
Leukotriene C(4) transporter (LTC4 transporter) ;ATP-binding cassette sub-family C member 1 ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Function:
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MALRGFCSAD | GSDPFWEWDV | SWNTSNPDFT | KCFQNTVLVW | VPCCYLWLCF |
100:
PFYFLYLSRH | DRGYIQMTYL | NKTKTALGFV | LWIVCWADLF | YSFWERSWGK |
150:
ILAPVFLVSP | TLLGITMLLA | TFLIQLERRK | GVQSSGIMLT | FWLIALLCAL |
200:
AILRSKIMTA | LKEDAEIDVF | RDVTFYIYFS | LVLIQLVLSC | FSDRPPLFSE |
250:
TIHDLNPCPE | SSASFLSRVT | FWWITGLMVR | GYRQPLESTD | LWSLNKEDTS |
300:
EQVVPVLVKN | WKKECAKSKR | QQRKITYSSK | DPAKPKGGSQ | VDVNEEAEVL |
350:
IVKTPQKERE | PSLFKVLYKT | FGPYFLMSFL | FKALHDLMMF | AGPEILKLLI |
400:
NFVNDKKAPD | WQGYLYTALL | FICACLQTLV | LHQYFHICFV | SGMRIKTAVI |
450:
GAVYRKALVI | TNSARKSSTV | GEIVNLMSVD | AQRFMDLATY | INMIWSAPLQ |
500:
VILALYLLWL | NLGPSVLAGV | AVMILMVPLN | AVMAMKTKTY | QVAHMKSKDN |
550:
RIKLMNEILN | GIKVLKLYAW | ELAFKDKVLA | IRQEELKVLK | KSAYLAAVGT |
600:
FTWVCTPFLV | ALSTFAVYVT | VDKNNILDAQ | KAFVSLALFN | ILRFPLNILP |
650:
MVISSIVQAS | VSLKRLRIFL | SHEELEPDSI | ERRPVKDGGG | ANSITVKNAT |
700:
FTWARSDPPT | LSGITFSIPE | GSLVAVVGQV | GCGKSSLLSA | LLAEMDKVEG |
750:
HVAIKGSVAY | VPQQAWIQND | SLRENILFGR | QLQERYYKAV | IEACALLPDL |
800:
EILPSGDRTE | IGEKGVNLSG | GQKQRVSLAR | AVYCDSDIYL | FDDPLSAVDA |
850:
HVGKHIFENV | IGPKGMLKNK | TRLLVTHSIS | YLPQVDVIIV | MTGGKISEMG |
900:
SYQELLARDG | AFAEFLRTYA | SGDQEQAEQD | DGLTGVSSPG | KEVKQMENGM |
950:
LVTDVAGKQL | QRQLSNSSSY | SGDVSRHHTS | TAELQKAGPK | NEDAWKLVEA |
1000:
DKAQTGQVKL | SVYWDYMKAI | GLFISFLSIF | LFLCNHVASL | VSNYWLSLWT |
1050:
DDPIVNGTQE | HTKIRLSVYG | ALGISQGITV | FGYSMAVSIG | GIFASRRLHV |
1100:
DLLQNVLRSP | MSFFERTPSG | NLVNRFSKEL | DTVDSMIPQV | IKMFMGSLFN |
1150:
VIGACIIILL | ATPIASIIIP | PLGLIYFFVQ | RFYVASSRQL | KRLESVSRSP |
1200:
VYSHFNETLL | GVSVIRAFEE | QERFIRQSDL | KVDENQKAYY | PSIVANRWLA |
1250:
VRLECVGNCI | VLFAALFSVI | SRHSLSAGLV | GLSVSYSLQV | TTYLNWLVRM |
1300:
SSEMETNIVA | VERLKEYSET | EKEAPWQIQE | MAPPSTWPQV | GRVEFRDYGL |
1350:
RYRENLDLVL | KHINITINGG | EKVGIVGRTG | AGKSSLTLGL | FRINESAEGE |
1400:
IIIDDINIAK | IGLHDLRVKI | TIIPQDPVLF | SGSLRMNLDP | FSQYSDEEVW |
1450:
TSLELAHLKD | FVSGLPDKLN | QECAEGGENL | SVGQRQLVCL | ARALLRKTKI |
1500:
LVLDEATAAV | DLETDDLIQS | TIRTQFDDCT | VLTIAHRLNT | IMDYTRVIVL |
1531:
DKGEIRECGQ | PSDLLQQRGL | FYSMAKDAGL | V
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Mouse
Dog
Bovine
ELISA Kit for Dog Multidrug resistance-associated protein 1
ELISA Kit for Dog Multidrug resistance-associated protein 1
ELISA Kit for Dog Multidrug resistance-associated protein 1
ELISA Kit for Dog Multidrug resistance-associated protein 1
ELISA Kit for Dog Multidrug resistance-associated protein 1
ELISA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
CLIA Kit for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Polyclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Monoclonal Antibody for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
Protein for Dog Multidrug resistance-associated protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;VARIANT SER-149
strain :
Beagle .
tissue :
Heart .
tissue :
Kidney .